Jagdeo Lab - UC Davis
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IFN-γ receptor-deficient donor T cells mediate protection from graft-versus-host disease and preserve graft-versus-tumor...

Sun, K Hsiao, Hh Li, M Ames, E Bouchlaka, M Welniak, La Hagino, T Jared Jagdeo Pai, Cc Chen, M ...

Published in The Journal of Immunology

Graft-versus-host disease (GVHD) is a major complication of allogeneic bone marrow transplantation. It has been previously reported that lung GVHD severity directly correlates with the expansion of donor Th17 cells in the absence of IFN-γ. However, the consequence of Th17-associated lung GVHD in the presence of IFN-γ has not been well characterized...

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